Microneedling Glide Options: Customizing Your Skin Rejuvenation Experience
At Aligned Aesthetics Co., microneedling is one of our favorite tools for improving skin texture, tone, and radiance. But what truly sets your treatment apart is the glide medium—the product used during microneedling that not only allows the device to move smoothly but also delivers high-performance ingredients deep into the skin.
We offer four distinct glide options, each with its own unique benefits. Hyaluronic acid is included with every microneedling treatment, while the other three are available as optional, add-on, alternatives to further personalize your experience. Whether you're new to microneedling or ready to level up your results, this guide will help you choose what’s right for your skin.
Hyaluronic Acid: The Hydration Hero
Included in every microneedling session
If you want a gentle, universally tolerated option, hyaluronic acid (HA) is the go-to. HA is naturally found in the body and is beloved for its ability to attract and hold moisture in the skin. This simple, soothing choice enhances hydration and plumpness without the risk of irritation.
Downtime: Expect standard microneedling downtime—typically 24 to 72 hours of redness, dryness, or mild flaking.
Best for: First-time microneedling patients, dry or sensitive skin, young skin, or anyone seeking a refreshed, glowing complexion.
Key Benefits:
Deep hydration
Enhanced skin smoothness
No risk of reaction
PRP (Platelet-Rich Plasma): Your Body’s Own Regenerator
Add-on option
PRP is our most popular glide upgrade—and for good reason. It’s autologous, meaning it's made from your own blood. After a quick blood draw, we isolate your platelet-rich plasma, which is packed with a comprehensive blend of growth factors that may promote collagen production and accelerate healing. When used during microneedling, PRP may supercharge the regenerative effects of the treatment using your body’s own natural resources.
Downtime: PRP may reduce post-treatment redness and speed recovery, and shorten typical downtime.
Best for: Those looking for natural, regenerative results, especially for aging skin, acne scars, or poor skin tone.
Key Benefits:
Uses your own biology (autologous = reduced risk of reaction)
May boost collagen and elastin production
May speed healing and reduces inflammation
Ariessence PDGF+:
Concentrated Growth Factors
Add-on option
Ariessence PDGF+ is an advanced glide option formulated with platelet-derived growth factor (PDGF) that works to stimulate collagen, elastin, and cellular repair. Unlike PRP, which uses your own platelets, Ariessence provides a concentrated, lab-cultured form of this powerful growth factor that can be as much as 300,000x more concentrated in PDGF than your own PRP. By fueling the skin’s regenerative processes, Ariessence may help accelerate healing, support tissue repair, and enhance overall skin quality after microneedling.
Downtime: Ariessence PDGF may reduce post-treatment redness and speed recovery, and shorten typical downtime.
Best for: Patients seeking firmer, smoother skin with a focus on repair and recovery—particularly those interested in growth factor technology but not wanting a blood draw.
Key Benefits:
Delivers concentrated platelet-derived growth factors directly to the skin
May stimulate collagen and elastin for firmer, more youthful results
May speed healing and reduce redness, offering a consistent alternative to PRP without a blood draw
VAMP by Prollenium: The Nutrient-Dense Rejuvenator
Add-on option
VAMP stands for Vitamins, Amino Acids, Minerals, and PDRN, creating a comprehensive nutrient cocktail that may support long-term skin health. One of the standout ingredients—PDRN (polydeoxyribonucleotide)—is a powerful regenerative compound derived from salmon DNA, known for its ability to boost skin healing, elasticity, and overall quality.
Downtime: VAMP may decrease downtime due to its reparative ingredients—many patients experience faster recovery and less post-treatment inflammation.
Best for: Stressed, aging, or depleted skin in need of nourishment and recovery.
Key Benefits:
PDRN from salmon DNA may support powerful cellular regeneration
Vitamins and minerals may restore skin vitality
May boost elasticity, tone, and overall resilience
PRX8 by Induction Therapies: Exosomes + Retinol Innovation
Add-on option
PRX8 is a high-performance glide medium that blends plant-derived exosomes with all-trans retinol. Exosomes act as cellular messengers, helping your skin communicate more effectively to regenerate and repair. When paired with retinol, they carry this potent active deeper into the skin, often resulting in a visible peel in the days following treatment. This makes PRX8 a powerful option for targeting pigmentation, fine lines, and texture issues.
Downtime: Expect increased downtime due to the enhanced delivery of retinol—peeling, flaking, and sensitivity may occur for up to a week post-treatment.
Best for: Those with prior microneedling experience looking for more dramatic resurfacing and skin rejuvenation.
Key Benefits:
Deep dermal delivery of retinol for enhanced peeling and renewal
Exosomes may improve cellular repair and collagen stimulation
Brighter, smoother, and more even-toned skin
Which Glide Medium Is Right for You?
Microneedling is not a one-size-fits-all treatment—and neither is the glide medium. Every session includes hyaluronic acid for hydration and skin support, while PRP, PDGF+, VAMP, and PRX8 are available as customizable add-ons. Microneedling is best as a series of 3 or more so please feel free to try out these different options throughout your series.
Whether you're seeking faster recovery, more dramatic results, or targeted skin correction, we’ll help you choose the right glide for your skin’s needs and your lifestyle.
Ready to customize your glow? Book a consultation and let’s build a microneedling plan that’s perfectly aligned with your skin.
